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Myeloid differentiation architecture of leukocyte transcriptome dynamics in perceived social isolation

Steven W. Cole, John P. Capitanio, Katie Chun, Jesusa M. G. Arevalo, Jeffrey Ma, John T. Cacioppo, ‘Myeloid differentiation architecture of leukocyte transcriptome dynamics in perceived social isolation’, http://www.pnas.org/content/112/49/15142, PNAS Online (October 21, 2015).

Social isolation

Analyses identify neuroendocrine-related alterations in myeloid cell population dynamics as a key mediator of CTRA transcriptome skewing, which may both propagate perceived social isolation and contribute to its associated health risks.

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